We dug into our own data to find which companies are using Microsoft 365 in production. We also asked engineers working in these companies to tell us how they're using Microsoft services, and what their major focus is right now (ie. AI pilots). Here are real-world examples of how the biggest companies in the world are using Microsoft 365.
Healthcare · New Brunswick, NJ · Microsoft 365
Microsoft 365
Microsoft Teams
SharePoint Online
Microsoft Copilot
Power Platform
Viva
Johnson & Johnson is one of the world's most recognisable healthcare companies, making everything from medicines and vaccines to surgical robots and contact lenses. Around 120,000 people work there across the globe.
Microsoft 365 Copilot is a major bet for J&J right now, and they've built a dedicated team around making it work at scale. The focus is on Copilot Agents, which are AI assistants that can do things on your behalf: summarise documents, pull information from internal systems, kick off approval workflows, answer questions based on company data. J&J is building these agents, deciding which ones are safe to use, and making sure they're deployed in a controlled way across the business.
That last part matters a lot in a company like J&J. Healthcare companies operate under strict rules about how data is handled, how clinical processes are documented, and how financial records are kept. Before any AI tool touches that kind of information, it has to be carefully reviewed and approved. The practice is responsible for making sure that happens, and for tracking down any AI agents that employees build and deploy without going through the proper process.
To help employees actually get value from Copilot day to day, J&J also runs an internal community through Microsoft Viva Engage, which is a social network built into Microsoft 365. Employees use it to share tips, ask questions, and show each other what Copilot can do in their specific jobs.
Banking · Amsterdam, Netherlands · Microsoft 365
Microsoft 365
Microsoft Teams
SharePoint Online
Exchange Online
OneDrive
Microsoft Purview
Microsoft Copilot
ABN AMRO is one of the largest banks in the Netherlands, serving personal, business, and corporate customers across the country and internationally.
Microsoft 365 is the digital workplace platform for the bank's 30,000 employees, and ABN AMRO runs a dedicated M365 DevOps team responsible for it end-to-end. That framing is deliberate: they treat M365 as a product platform to be continuously developed and governed, not just maintained.
The team's scope is broad. They own Teams, Exchange Online, SharePoint Online, and OneDrive, and are responsible for both the engineering depth and the platform governance that keeps those services running cleanly at scale. That includes security and compliance work using Microsoft Purview and Entra ID, automation through PowerShell and Azure pipelines, and managing licensing and provisioning across the tenant.
What's notable is the Copilot dimension. ABN AMRO is actively working on Microsoft 365 Copilot capabilities, which means the M365 platform team is responsible not just for the collaboration infrastructure but for how AI-assisted tooling gets deployed and governed across the bank. In a regulated financial institution, that involves careful attention to data access controls, compliance boundaries, and how the AI features interact with sensitive banking data.
The team operates across the Netherlands with members also based in India, reflecting how seriously ABN AMRO has invested in the platform engineering practice behind their digital workplace.
Financial Services · New York, NY · Microsoft 365
Microsoft 365
Microsoft Teams
SharePoint Online
Exchange Online
Microsoft Purview
Microsoft Copilot
Power Platform
Morgan Stanley is one of the world's leading investment banks and financial services firms, operating across wealth management, investment banking, and securities in more than 40 countries.
Microsoft 365 is the collaboration platform for the firm's 80,000 employees, and Morgan Stanley has invested significantly in the engineering practice behind it. Their M365 team manages the core platform: SharePoint Online, Teams, Exchange Online, and Microsoft Purview for compliance and data protection.
What makes Morgan Stanley's story distinctive right now is Copilot. The firm is actively building out Microsoft 365 Copilot integration, and the engineering practice is responsible not just for deploying it but for extending it.
That means configuring Copilot connectors and agents, which are ways of giving the AI assistant access to internal data sources and automating workflows on behalf of employees. In a financial institution, that kind of integration requires careful attention to data governance, because what information Copilot can access and how it uses it has real compliance implications.
The practice also manages Microsoft Purview configurations including sensitivity labels, data loss prevention policies, and eDiscovery capabilities, all of which become more important as AI tooling gets layered on top of the collaboration environment.
For a firm whose business depends on the integrity of its information and the trust of its clients, getting the governance layer right on Copilot is not an afterthought. Morgan Stanley is treating it as a core engineering problem.
Financial Services · Tokyo, Japan · Microsoft 365
Microsoft 365
Microsoft Teams
SharePoint Online
OneDrive
Microsoft Copilot
Power Platform
Viva
MUFG (Mitsubishi UFJ Financial Group) is one of the world's largest financial groups, with more than 120,000 employees across operations in over 40 markets globally.
Microsoft 365 is a core part of how MUFG's workforce operates, and the firm has built a dedicated M365 adoption and enablement team around it. The focus is not just on keeping the platform running but on making sure employees actually get value from it, particularly from Microsoft 365 Copilot and Power Platform.
The M365 adoption team runs a structured Copilot rollout program. That includes a champions network, where employees across business units are trained to support their colleagues in using Copilot and Power Platform tools. It also includes training sessions, office hours, quick-start guides, and a self-service knowledge hub built on SharePoint. The goal is to help employees move from knowing Copilot exists to using it in their daily work in ways that actually save time.
The Copilot Studio dimension is particularly notable. MUFG is building AI agents, which are automated assistants that can carry out specific tasks on behalf of employees using data from across the M365 environment. Deploying these in a regulated financial institution requires careful governance: the M365 team is responsible for setting the boundaries around what data the agents can access, how compliance requirements are met, and how responsible AI guidelines are communicated to employees.
On top of the adoption work, the M365 team also runs the underlying platform across Teams, SharePoint, OneDrive, and Viva, with usage analytics feeding back into continuous improvement of both the platform and the programs built around it.
Aerospace · Kent, WA · Microsoft 365
Microsoft 365
Microsoft Teams
Microsoft Purview
Entra ID
Microsoft Copilot
Blue Origin is an aerospace company building reusable rockets and space vehicles with the goal of making access to space routine and affordable.
Running a company that designs and operates launch vehicles requires the same discipline in its digital infrastructure as in its engineering. Blue Origin has a dedicated senior engineering practice responsible for Microsoft 365 and Identity and Access Management, treating both as interconnected systems that underpin collaboration and security across the company.
The M365 side covers the full collaboration stack, with a focus on ensuring the platform is reliable, secure, and continuously improving. The identity side is equally significant: the team owns the lifecycle of how employees get access to systems, from the moment they join to the moment they leave, using Entra ID and a Zero Trust security model. Zero Trust means the system never assumes a user or device is trusted just because it's inside the company network. Every access request is verified.
The team also partners closely with cybersecurity, infrastructure, and HR systems to keep identity and access tightly governed. That matters in an aerospace company with strict regulatory and export control requirements, where the wrong person having access to the wrong system is a serious compliance risk.
There's also an AI dimension. Blue Origin is actively incorporating AI into how their M365 and identity solutions are designed and operated, looking for ways to use it to improve system outcomes rather than just automate routine tasks.
Financial Technology · San Jose, CA · Microsoft 365
Microsoft 365
Microsoft Teams
Teams Phone
SharePoint Online
Exchange Online
Microsoft Copilot
PayPal is one of the world's largest digital payments platforms, processing billions of transactions a year across roughly 200 markets.
Microsoft 365 is the collaboration platform for PayPal's global workforce, and the company has built a dedicated engineering practice around it. The scope covers Teams, SharePoint Online, Exchange Online, and Microsoft 365 Copilot, with a focus on keeping the platform secure, well-governed, and useful at scale.
The voice and telephony side is particularly developed. PayPal's M365 engineers manage Teams Phone, including call routing configuration, voice policies, and security and compliance features specific to voice communications. That level of investment in Teams Phone suggests PayPal has moved a meaningful part of its enterprise telephony onto the platform.
The Copilot angle is also active. PayPal is incorporating Microsoft 365 Copilot into its M365 environment, with engineers expected to understand how the AI assistant integrates with Teams, SharePoint, and Exchange, and how to apply it to IT operations.
Governance and compliance round out the picture. The engineering practice manages policies, data governance, and regulatory adherence across the full M365 stack, which for a company that handles payments and financial data at scale carries real weight.
Food & Beverage · Purchase, NY · Microsoft 365
Microsoft 365
Microsoft Teams
SharePoint Online
Power Platform
Microsoft Copilot
Viva
PepsiCo is one of the world's largest food and beverage companies, with brands including Pepsi, Lay's, Gatorade, Quaker, and Tropicana sold across more than 200 countries. Their global workforce runs to roughly 290,000 people.
Microsoft 365 is the collaboration and productivity platform for all of them, and PepsiCo has invested heavily in making the most of it. Their M365 architecture practice covers Teams, SharePoint, Exchange Online, Power Platform, and an expanding AI layer built on Microsoft 365 Copilot and Copilot Studio.
One of the most interesting parts of PepsiCo's approach is how they handle automation. Rather than having a central IT team build every workflow and application, PepsiCo gives employees across the business the tools and guardrails to build their own, using Microsoft's Power Platform. A dedicated Center of Excellence sets the standards, manages the governance, and makes sure things don't get out of hand. The goal is to spread the ability to automate work broadly, not bottleneck it.
The AI layer is equally active. PepsiCo is building AI assistants using Copilot Studio that can carry out tasks on behalf of employees, and the architecture team is responsible for making sure those tools are deployed safely, with clear rules around what data they can access and how they're used inside a regulated global company.
When PepsiCo acquires another company, the M365 team also handles the technical side of bringing that company's collaboration environment into PepsiCo's. At their scale, that is a significant and ongoing part of the job.
Beverage Manufacturing · Milan, Italy · Microsoft 365
Microsoft 365
Microsoft Teams
SharePoint Online
Exchange Online
OneDrive
Microsoft Copilot
Viva
Campari Group is the Italian company behind some of the world's most recognisable drinks: Aperol, Campari, Wild Turkey bourbon, Grand Marnier, and Courvoisier cognac. Founded in Milan in 1860, they sell across more than 190 countries with around 5,000 employees and 25 production plants worldwide.
Running a global drinks business means keeping thousands of people connected across factories, offices, and distribution networks on multiple continents. Microsoft 365 is how Campari does that, and they have a dedicated Global M365 Architect whose job is to own the platform end to end.
One of the more interesting aspects of Campari's setup is how seriously they treat identity. Every employee in the company has a digital identity that determines what systems they can access, what files they can see, and what they're allowed to do. Campari connects their M365 environment to their HR platform so that when someone joins, moves between teams, or leaves, their access updates automatically. At 5,000 employees across 26 countries, keeping that accurate is a real engineering problem.
The Copilot angle is also live. Campari is rolling out Microsoft 365 Copilot and treating it as a genuine shift in how employees work, not just a new feature to switch on. The M365 Architect owns the roadmap for that, alongside the governance rules that determine how AI tools interact with company data.
For a company that has been making drinks for over 160 years, the investment in getting digital collaboration right is a telling sign of how central these tools have become to how modern enterprises actually run.
Financial Services · New York, NY · Microsoft 365
Microsoft 365
Microsoft Teams
SharePoint Online
Exchange Online
OneDrive
Microsoft Purview
Power Platform
Intune
Microsoft Copilot
Goldman Sachs is one of the world's most powerful investment banks, helping corporations, governments, and institutions raise money, manage risk, and invest. Around 70,000 people work there across offices in every major financial city on the planet.
Keeping that many people connected and productive, while also keeping the firm's information secure, is a serious engineering challenge. Microsoft 365 is how Goldman Sachs does it, and they've built a dedicated engineering practice to own the platform end to end: Teams, SharePoint, Exchange Online, OneDrive, Microsoft Purview, Power Platform, and Windows 365.
The financial services environment shapes everything. Goldman Sachs operates under some of the strictest regulatory requirements of any industry. That means every new Microsoft feature has to be carefully evaluated before it reaches employees. It can't just be switched on because Microsoft released it. The engineering practice owns that process, deciding what gets adopted, when, and with what controls in place.
Copilot and AI are part of the picture too. Goldman Sachs is actively working to bring Microsoft 365 Copilot and Power Platform capabilities to its workforce, with the engineering team making sure that AI tools are deployed in a way that meets the firm's compliance and data protection obligations.
One thing that stands out is the device layer. Goldman Sachs's M365 practice also covers Intune, which is Microsoft's system for managing the laptops and phones employees use to connect to company systems. At a firm where a single data leak can have enormous consequences, controlling what devices can access the network and how they're configured is just as important as any other security measure.
Pharmaceutical · Basel, Switzerland · Microsoft 365
Microsoft 365
Microsoft Teams
SharePoint Online
Exchange Online
OneDrive
Power Platform
Viva
Microsoft Copilot
Novartis is one of the world's largest pharmaceutical companies, developing medicines for conditions ranging from cancer to heart disease to rare genetic disorders. They employ around 83,000 people across more than 100 countries.
Getting new medicines to patients requires thousands of scientists, researchers, regulators, and commercial teams working together across the globe. Microsoft 365 is the platform that connects all of them, and Novartis has invested in running it at a level that matches the scale and complexity of the business.
Their M365 practice covers the full suite: Exchange, SharePoint, Teams, OneDrive, Power Platform, Viva, and Microsoft 365 Copilot. The practice also owns Novartis's entire commercial relationship with Microsoft, including enterprise licensing agreements, Copilot licensing, and negotiations over what the company pays and gets in return. At that scale, the licensing bill alone is a significant financial exercise.
The Copilot rollout is a major focus. Novartis is actively deploying Microsoft 365 Copilot across its workforce and measuring the value it delivers. That includes building the data governance frameworks that determine what information the AI can access and ensuring employees are using it in a way that meets pharmaceutical regulatory requirements.
For a company whose work involves sensitive clinical data, intellectual property, and strict regulatory obligations, getting the governance layer right on AI tools is not optional. Novartis is treating it as a core part of how the platform is run.
Technology & E-Commerce · Seattle, WA · Microsoft 365
Microsoft 365
SharePoint Online
OneDrive
Microsoft Teams
Amazon is one of the world's largest companies, spanning e-commerce, cloud computing, logistics, and entertainment. Over 750,000 people work there globally.
Microsoft 365 is part of how Amazon's internal workforce stays connected and productive, and Amazon runs a dedicated engineering practice around SharePoint Online and OneDrive in particular. The practice is responsible for building and operating the document collaboration and file storage systems that employees use every day, at a scale that few organisations in the world can match.
What makes Amazon's story particularly interesting is one specific application: Amazon Leo, the company's satellite internet project. Amazon Leo is building a constellation of low Earth orbit satellites to bring affordable broadband to underserved communities worldwide. The project operates in a GCC High environment, which is a specially hardened, US government-compliant version of Microsoft 365 used by defence contractors and organisations with strict national security requirements. Managing M365 in that environment requires a separate engineering practice and a much higher bar for security, compliance, and change control.
The combination of Amazon's internal M365 engineering practice and the GCC High deployment for Leo makes for a distinctive story: one of the world's most technically ambitious companies running Microsoft 365 across two very different operating environments at the same time.
Banking · Amsterdam, Netherlands · Microsoft 365
Microsoft 365
Microsoft Teams
SharePoint Online
OneDrive
Exchange Online
ING is a Dutch bank with around 70,000 employees serving customers across more than 40 countries. They're known as one of the more digitally progressive banks in Europe, and that ethos carries through into how they run their internal technology.
Microsoft 365 is ING's global collaboration platform, and they run a dedicated engineering practice around it. The team is responsible for keeping M365 services running reliably, securely, and at the pace of a bank that moves fast.
One thing that stands out about ING's approach is their relationship with Microsoft. The M365 engineering team works directly with Microsoft's product teams, not just as a customer using what's available, but as a partner feeding back on features and requesting improvements. For a bank of ING's size, that kind of direct engagement with the vendor gives them influence over how the platform evolves.
The security dimension is also notable. ING's M365 practice actively manages endpoint vulnerabilities, meaning they track security weaknesses across the devices employees use, coordinate how and when fixes are rolled out, and communicate with affected users. In a regulated banking environment where a security gap can have serious consequences, that level of operational discipline around device management is part of running M365 responsibly.
Airlines & Aviation · Paris, France · Microsoft 365
Microsoft 365
Microsoft Teams
SharePoint Online
Microsoft Copilot
Power Platform
Viva
Air France-KLM is the Franco-Dutch airline group behind Air France, KLM, and Transavia, operating one of the largest long-haul networks in the world from Europe. Around 80,000 people work across the group.
All 80,000 of those employees use Microsoft 365 every day, across Teams, SharePoint, Outlook, and Viva. That's a significant platform to run, and the group has invested seriously in the engineering practice behind it.
What makes Air France-KLM's story particularly interesting right now is where they are with AI. Their Copilot and AI architecture practice is being built from the ground up. AI agents, Copilot Studio, governance, adoption, and security are all being designed and constructed at the same time, across a business that spans flight operations, maintenance, HR, finance, and customer service.
The practice is responsible for building Copilot Studio agents tailored to different parts of the business, connecting them to internal systems using Azure AI and Power Platform, and ensuring everything meets European data protection rules. The governance layer is a particular focus: determining which data the AI tools can access, how agents are approved before they go live, and how responsible AI principles are applied across the group.
Air France-KLM also works directly with Microsoft as part of this rollout, collaborating on how the platform evolves to meet the specific needs of a major airline operating across dozens of countries.